The authors did not receive support from any organization for the submitted work. and JavaScript. sharing sensitive information, make sure youre on a federal Expeditious removal of the offending agent is critical to the resolution of symptoms, but care must be taken to not open the incision(s). Dowson, C. C., Gilliam, A. D., Speake, W. J., Lobo, D. N. & Beckingham, I. J. There are some reports in the literature regarding Dermabond associated contact dermatitis. and Get the most important science stories of the day, free in your inbox. Although the clinical studies showed equivalent results between 2-octyl cyanoacrylate and n-butyl cyanoacrylate topical skin adhesives26,27, the results of the animal studies showed that n-butyl cyanoacrylate is inferior in adhesion and wound-bursting strength than 2-octyl cyanoacrylate and would have led to less use of n-butyl cyanoacrylate than 2-octyl cyanoacrylate as a topical skin adhesive28,29. 2022 Copyright OAT. Park, Y. H., Song, J. H., Choi, G. W. & Kim, H. J. Allergic Contact Dermatitis to Dermabond Prineo After Elective - PubMed Proc (Bayl Univ Med Cent). Csections in 2010 & 2015-had reaction to dermabond after 2010 c section. Unable to load your collection due to an error, Unable to load your delegates due to an error. Laparosc. official website and that any information you provide is encrypted Skin patch testing performed three years after initial presentation was positive for ethyl cyanoacrylate. Its a good idea to let your doctor know if you develop a rash after surgery. It may be from the glue or adhesive used to close the wounds, or from antibiotic ointments applied to the wound to prevent infection. Bouten, P. J. et al. endstream endobj 122 0 obj <>>>/Lang(en-US)/Metadata 119 0 R/Names 123 0 R/Outlines 94 0 R/Pages 118 0 R/Type/Catalog/ViewerPreferences<>>> endobj 123 0 obj <> endobj 124 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/Tabs/W/Thumb 113 0 R/TrimBox[0.0 0.0 595.276 841.89]/Type/Page>> endobj 125 0 obj [126 0 R] endobj 126 0 obj <>/Border[0 0 0]/H/N/Rect[445.858 120.461 538.761 109.669]/Subtype/Link/Type/Annot>> endobj 127 0 obj <> endobj 128 0 obj <> endobj 129 0 obj [/ICCBased 153 0 R] endobj 130 0 obj <> endobj 131 0 obj <> endobj 132 0 obj <> endobj 133 0 obj <> endobj 134 0 obj <>stream the suspicion of an allergic reaction to Dermabond and recommended application of a thin topical layer of hydrocortisone 1% to affected areas 2-4 times per day. In addition, in joint arthroplasty surgery, Michalowitz et al.23 reported an incidence of 1.8% in 281 patients and Durando et al.24 reported 1.7% in 912 patients. Interestingly, Nakagawa et al.25 reported a 7.0% incidence of ACD in 100 patients who underwent breast reconstruction surgery. Once applied, this film is left to dry and usually lasts five to 10 days on the skin. 2017 May;45(2):195-198. doi: 10.1080/00913847.2017.1283208. Severe dermatitis from Dermabond (R) surgical glue Did you have pelvic pain following your hysterectomy? Michalowitz, A., Comrie, R., Nicholas, C., Wagner, M. & Kehoe, J. 2015;73(4):195-221. Medication for eczema and dermatitis. Her incisions were closed with Dermabond. Please enable it to take advantage of the complete set of features! Dermabond is not used on areas such as the eyes and mouth. Skin patch testing can be utilized to confirm clinical suspicion for an allergic reaction to Dermabond. At-home therapies for eczema and dermatitis. 18, 1927 (2004). (n.d.). I had a rash covering my whole abdomen and anywhere they put that stuff, as well as on my thighs. Wright JD, Ananth CV, Lewin SN, Burke WM, Lu YS, et al. They will examine the rash itself, noting its size, shape, color, severity, and other characteristics. There are two main causes of this type of rash: Contact your doctor immediately if your wound or the area around it becomes red or discolored, hot, or itchy, or if green, yellow, or cloudy discharge drains out. HysterSisters.com is a massive online community with over 475,000 members and over 5 million posts. Patients were followed up between the first and second week after surgery, and surgical wounds were inspected by orthopedic surgeons. ~%_W+ What Causes White Spots to Form on Your Nipple? Interv. and After approval from the local ethics committee (Korea University Guro Hospital Institutional Review Board, No. . Past medical history is significant for stage 0 DCIS, chronic hypertension and migraine headache. Learn about hysterectomy types and diagnosis. 0000031623 00000 n 7 status post total laparoscopic hysterectomy and bilateral salpingo-oophorectomy with sudden onset of erythema and pruritus around all four port site incisions (Figure 1). Am J Otolaryngol. Lee E, Elzomor A, Zwemer C, Chen A, Thakkar PG. 0000012232 00000 n Prehosp Disaster Med. For full access to this pdf, sign in to an existing account, or purchase an annual subscription. Krishnan, R., MacNeil, S. D. & Malvankar-Mehta, M. S. Comparing sutures versus staples for skin closure after orthopaedic surgery: systematic review and meta-analysis. As no definite factors related to the development of allergic contact dermatitis to topical skin adhesives are known, the variables that have been suspected to correlate with type IV hypersensitivity were included in the investigation, along with patient characteristics20,21,22. The uterus was removed and then the vaginal cuff was closed with 0-vicryl suture. Slider with three articles shown per slide. 0000009330 00000 n Pamela L. Scheinman, Marc Vocanson, Ari M. Goldminz, Hyo-Eun Kwon, Hye-Jin Ahn, Min Kyung Shin, Stephan Weidinger, Lisa A. Beck, Alan D. Irvine, Young Jae Kim, Dong Jun Lim, Chong Hyun Won, Vasco Silva-Neves, Vitor Hugo, Miguel Pais-Vieira, Mario Mastrocola, Georg Matziolis, Henk Eijer, Julie Bruce, Blessing Oyedemi, Freya Harrison, Young-Je Kim, Mi Ji Choi, Beom Joon Kim, Raiyyan Aftab, Vikash H. Dodhia, Ryckie G. Wade, Scientific Reports Dermabond () surgical glue had been applied to the skin at wound closure; the glue residue remained on the skin for several days. Nakagawa, S. et al. Bethesda, MD 20894, Web Policies Cochrane Database Syst Rev. This site needs JavaScript to work properly. Given the case history, the patient was likely sensitized to Dermabond from prolonged exposure to embedded Dermabond from a previous procedure. Lindstrom I, Suojalehto H, Henriks-Eckerman ML, Suuronen K (2013) Occupational asthma and rhinitis caused by cyanoacrylate-based eyelash extension glues. CAS Although the use of topical skin adhesives has increased as an alternative to conventional skin closure methods, studies on the incidence and risk factors of ACD to topical skin adhesives have been limited. Objective: To investigate the clinical characteristics of patients with ACD caused by Dermabond application. Careers. The surgeon and infectious disease physician agreed that her erythema was an allergic reaction to the Dermabond. According to the patient, the Dermabond was placed haphazardly during this tubal ligation and reportedly was present within a chronically draining wound for four months. 2019 Sep/Oct;30(5):314-322. doi: 10.1097/DER.0000000000000514. Hysterectomy Recovery (post hysterectomy). None of the variables was found to increase the risk of ACD. J.S.C. Sheikh, Mohammad Tafazul Percutan Tech. Allergic reactions to 2-octyl cyanoacrylate (Dermabond; Ethicon, Somerville, NJ) are rare in the medical literature; there is only one published report.1 There are, however, scattered anecdotal reports of allergies to Dermabond on the Internet. Comparison of wound-bursting strengths and surface characteristics of FDA-approved tissue adhesives for skin closure. We aim to bring about a change in modern Published reports of an allergic reaction to Dermabond, Time elapsed from surgery to onset of allergic reaction (days), Unreported; each with 1-3 prior orthopedic surgeries, Yes, 1-year prior for tubal ligation with haphazard application and prolonged embedded application, Octyl-2 cyanoacrylate and Prineo self-adhering mesh ++, Dermabond& 2-hydroxyethyl methacrylate +++, Dermabond & N-2-butyl cyanoacrylate +++, Neurosurgery, Laparoscopic General Surgery, None for first case & yes for other 3 cases, Dermabond, Dermabondwith chlorhexidine, and Dermabond with povidone iodine +++. 15, 689695 (2004). Oxford University Press is a department of the University of Oxford. If an allergic reaction is encountered, Dermabond should be removed with petroleum jelly or acetone. Close-up view of erythema surrounding the right lower abdominal 5-mm trocar site on post-operative day 7. To date, ACD to topical skin adhesives has been continuously reported in case reports of sporadic events, but systematic studies on their incidence and risk factors have been limited. However, considering that the mechanism of type IV hypersensitivity does not differ depending on the body part and the used site was not a factor affecting the occurrence of the ACD17,22, it is judged that the bias in the study population will not affect the generalization of the study results. 2-octyl cyanoacrylate; Dermabond; allergic contact dermatitis; ethyl cyanoacrylate; gel nails, (meth)acrylate; tissue adhesive. 2020. Correspondence to 2nd ed. Rabah, Sari Monzer Prehosp Disaster Med. The surgeon and infectious disease physician agreed that her erythema was an allergic reaction to the Dermabond. In some cases, your doctor may want to perform a skin biopsy as well. Immunol. Parkerson, Jamie You are using a browser version with limited support for CSS. While your rash may resolve quickly, you may need to change bandages or medications your doctor has prescribed. Additional options for both kinds of post-surgical rashes include: Your doctor might decide to prescribe medications to treat your rash. & Hartman, E. H. Octyl-2-cyanoacrylate tissue glue (Dermabond) versus Monocryl 6 0 Sutures in lip closure. Contact with anionic substances, such as blood, initiates the polymerization reaction and the material quickly sets to form a dry solid film that holds apposed skin edges together [6]. Medicine 99, e20573 (2020). Thus, allergic reactions should only increase as laparoscopic and robotically assisted hysterectomy replace open abdominal and vaginal techniques. Glob. Surgical history is significant for partial left mastectomy performed two years prior and L5 laminectomy fifteen years before presentation. 0000105281 00000 n Cell Mol. Gonzalo-Garijo MA, Perez-Calderon R, Perez-Rangel I, Sanchez-Vega S, Constantino JA (2009) Contact dermatitis after orthopaedic surgery. and J.W.C. Surgical wound closure by staples or sutures? 0000044744 00000 n National Library of Medicine Durando, D. et al. redness or discoloration, or visible rash, skin blisters that may drain fluid (especially if you scratch at the rash), a rash that appears quickly, spreads, and covers all or most of your body, shortness of breath or difficulty breathing, antibiotics if your rash is caused by an infection, prescription anti-inflammatory medications, a replacement medication if your rash was caused by a drug allergy. Clipboard, Search History, and several other advanced features are temporarily unavailable. Responsibilities, Copyright & License Nakagawa, Shiho Her itching ceased within hours of these final treatments. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Adv. Positive reactions to ethyl cyanoacrylate adhesive (Aron Alpha) occurred in seven of nine patients, to ethyl cyanoacrylate 10% pet. Feature Flags: { Occupational asthma has also been linked to exposure to cyanoacrylate adhesives used to affix sculpted acrylic artificial nails in beauty salons [28]. sustainable solutions for society. & Thode, H. C. Jr. A review of the literature on octylcyanoacrylate tissue adhesive. There has never been a reported case resulting from gynaecologic surgery until now. In addition, the sutureless closure has become a marketing tool for surgeons. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Allergic Contact Dermatitis after Repeated Exposure to Dermabond (TM.) If allergic dermatitis is the diagnosis, avoiding the irritant is the first line of defense. Your doctor should be notified of any symptoms of infection, so treatment can begin immediately. Figure 1. After DERMABOND PRINEO System is applied, how will the surgeon assess whether the wound is healing Federal government websites often end in .gov or .mil. Blanchet, Nadia J. Arthroplasty 32, 37423747 (2017). Ferguson, J. W., Tripathi, D. & Hayes, P. C. Review article: The management of acute variceal bleeding. scholarly communications through the effective use of editorial and This article describes a severe allergic reaction to Dermabond following breast augmentation/mastopexy. volume11, Articlenumber:23762 (2021) J. The patient was advised to remove the skin adhesive with petroleum jelly and acetone. What steps should be taken if a patient experiences a local reaction or hypersensitivity to .