what is polyethylene glycol in food

Epub 2022 Mar 24. Poly (ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. But is it safe to eat? More of a heavy duty polyethylene plastic is used in the freezer bags, as they need to be able to with stand extreme cold and still be able to protect the items within. Propylene glycol is a colorless, nearly odorless, thick liquid. Drug class: Laxatives. PEGylation is the act of covalently coupling a PEG structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEGylated protein. The real concern surrounding polyethylene glycol is three-fold: Despite a lack of studies or a clear picture of the exact impact PEG compounds have on our bodies, we do know that this compound can have some negative side effects. In rats, the median lethal dose is 9 grams per pound (20 g/kg). The https:// ensures that you are connecting to the For oral dosage form (powder for solution): Adults and children 17 years of age and older17 grams (g) once a day. Polyethylene glycol can be highly useful and is found in a wide range of products such as: One of the most widespread uses of PEG is in a class of medications known as osmotic laxatives, which are used to treat constipation. If you have any of these conditions, you could have dangerous or life-threatening side effects from polyethylene glycol 3350. The structure of PEG is commonly expressed as H(OCH2CH2)nOH.[3]. This article examines its benefits and side effects to determine how it affects your health. 2 Molecular weights of PEGs vary by time of the Advertising revenue supports our not-for-profit mission. The name may be followed by a number which represents the average molecular weight (e.g. MiraLAX usually produces a bowel movement in 1 to 3 days. Propylene glycol is from the family of alcohol. Xanthan Gum Is This Food Additive Healthy or Harmful? At molecular weights between 700 and 900, polyethylene glycol is a semisolid. 2023 Jan 28;11(2):282. doi: 10.3390/vaccines11020282. In this case, a rash may develop in sensitive people when their skin comes into contact with products that contain it, such as shampoo or moisturizer (6). Store at room temperature away from moisture and heat. Addition of a polyethylene glycol (PEG)-based laxative to a liquid that has been thickened with a starch-based thickener may counteract the thickening action, placing patients with dysphagia at a . An Analysis of the Italian National Spontaneous Adverse Drug Reaction Reporting System. Two patients developed anaphylaxis following intradermal test to PEG and 1 a systemic allergic reaction (without hypotension or respiratory distress) following PEG skin prick tests. Calzetta L, Chetta A, Aiello M, Frizzelli A, Ora J, Melis E, Facciolo F, Ippoliti L, Magrini A, Rogliani P. Vaccines (Basel). Walgreens found 1brand TEVA Cephalexin liquid . They vary in consistency from liquid to solid, depending on the molecular weight, as indicated by a number following the name. Please enable it to take advantage of the complete set of features! The choices you make on a day-to-day basis are the foundation of your well-being. Due to its chemical properties, it is also found in a wide variety of hygiene and cosmetic products. It can also be slit or spun into synthetic fibres or modified . While propylene glycol is generally considered safe, you may still choose to avoid it if you are allergic or you simply want to reduce your intake. It works by increasing the amount of water your intestine absorbs. In one report, an 8-month-old child suffered loss of heart function and subsequent brain damage after being treated with silver sulfadiazine cream that contained propylene glycol. Detailed Polyethylene glycol 3350 dosage information, Polyethylene glycol 3350 drug interactions. It is a solvent for food colors and flavors, and in the paint and plastics industries. Titanium dioxide: "A colorant commonly used in vitamins that is indigestible." 5. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. It is used to absorb extra water and maintain moisture in certain medicines, cosmetics, or food products. Keep from freezing. The polyethylene is used to make the plastic film that will eventually become the sandwich bags. For people with allergic dermatitis, it is best to avoid all sources of propylene glycol. Animal studies also demonstrate that very high doses of propylene glycol can rapidly decrease heart rate, cause low blood pressure and even cause the heart to stop (25, 26). He developed symptoms of toxicity, including non-responsiveness and irregular heart rhythms, but recovered after the vitamin solution was stopped (28). Polyethylene glycols (PEGs) or macrogols are hydrophilic polymers found in everyday products such as foods, cosmetics, and medications. Its not only impossible but also unnecessary to attempt to avoid PEG altogether. The food you buy from grocery stores can contain many ingredients. One of them developed severe unspecified neurological symptoms (30). On the other hand, polyethylene glycol (PEG) is a common inactive ingredient in foods, dietary supplements, and personal care items. By consuming a fresh, healthy, whole foods diet, you can avoid most sources without too much trouble. 2023 Healthline Media LLC. PEGs are considered inert (they do not react with other materials), and they are nontoxic. For cosmetic products, it stabilizes products keeping them from melting in high heat or freezing at lower temperatures. Propylene glycol is a colorless, odorless synthetic liquid that absorbs water. Polyethylene glycol identified in this section may be safely used in food in accordance with the following prescribed conditions: (a) Identity. A small percentage of people are allergic to propylene glycol and may need to avoid products containing it. The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds. Epub 2021 Feb 28. They are used as thickeners, softeners, moisture-carrying agents, penetration enhancers, and surfactants. The amount of propylene glycol found in a normal diet is not associated with any heart problems in children or adults. Clin Immunol. Typically, ethylene oxide macromolecules (Fig. Commonly called glycerol or glycerin, 1,2,3-propanetriol is the most important trihydroxy alcohol. 2023 Apr;46(4):343-355. doi: 10.1007/s40264-023-01277-5. Do not use it for more than 7 days unless your doctor has told you to. If you have any of these conditions, you could have dangerous or life-threatening side effects from polyethylene glycol 3350. sharing sensitive information, make sure youre on a federal After ingesting a food containing propylene glycol, about 45% of it will be excreted by the kidneys unchanged. Ingesting enough can cause death. However, as current intakes are estimated to be above the recommended level, it may be wise to reduce dietary sources where you can, especially as the primary sources are highly processed foods. Propylene glycol is a popular addition used to help process food and enhance its texture, taste, shelf life, and appearance. An alternative can usually be found. . Healthline Media does not provide medical advice, diagnosis, or treatment. You may report side effects to FDA at 1-800-FDA-1088. It is necessary to hold the growing polymer chain in solution in the course of the polycondensation process. Polyethylene Glycol 3350 And Electrolytes (Oral Route) Your gift holds . These symptoms disappeared within 6 hours (31). This enzyme is essential for the breakdown of propylene glycol (1, 9, 20). According to the World Health Organization, the acceptable amount is a maximum of 25 milligrams of propylene glycol per kilogram of your body weight., Toxicity from propylene glycol is rare. .mw-parser-output .ib-chembox{border-collapse:collapse;text-align:left}.mw-parser-output .ib-chembox td,.mw-parser-output .ib-chembox th{border:1px solid #a2a9b1;width:40%}.mw-parser-output .ib-chembox td+td{width:60%}, Polyethylene glycol (PEG; /plilin lakl, -l-, -kl/) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used. Is Polyethylene Glycol (PEG) Toxic? Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future. It is widely used as an additive in pharmaceuticals, cosmetics and food [ 1 ]. 1 PEG is nontoxic and has been approved for use as a food additive by the US Food and Drug Administration (FDA . About 45% of the compound gets out of the body through the kidneys unchanged. In the US, it can be used as a direct and indirect food additive. But the fact that its also an ingredient in antifreeze raises concerns about the possible side effects of eating any food contaminated with it. Pre-made, mass-distributed baked desserts such as brownies, cakes and cupcakes may also contain this chemical. Jill Carnahan, M.D., A.B.F.M., A.B.I.H.M., I.F.M.C.P., uses functional medicine to help people find the answers to the cause of their illness and the nutritional and biochemical imbalances that may be making them feel ill. Functional medicine is personalized medicine that deals with root cause of disease instead of just treating symptoms. What is Propylene Glycol? Stone Jr., MD, MPH, and colleagues at Vanderbilt University School of Medicine This article investigates what propylene glycol is, why it is used and whether it is dangerous to your health. This propylene is often used in making propylene oxide which, when hydrolyzed with water, gets the propylene glycol. This content does not have an Arabic version. No data were provided for table-top sweeteners. PEGs are also used in veterinary products. PEGs have many industrial, food and pharmaceutical uses. What Is Polyethylene Glycol? The characteristics of PEGs make them excellent materials for use in the pharmaceutical industry. Its non-toxic properties, solubility and ability to be rapidly removed make polyethylene glycol suited to a wide range of applications. Importantly, patients taking the White Rather it's a category of compounds in which polyethylene and glycol have been bonded together. It's used in many products because it helps them maintain their consistency, moisture, and texture.. The most common signs are skin reactions, dermatitis, and a rash on the face or the whole body., Increased risk of a heart attack: When propylene glycol is injected in high amounts, it leads to rapid heart rate, heart rhythm problems, or low blood pressure.. I am very allergic to both, the fact that it's in all most all of our antibiotics makes it worse. Propylene glycol also has other names, including: Sometimes people confuse it with ethylene glycol. The rest is broken down in the body into lactic acid (1, 14). Polyethylene glycol has a low toxicity and is used in a variety of products. It may take 1 or 3 days for this medicine to help you have a bowel movement. But polyethylene glycol can also be found in more inconspicuous places. Industry provided EFSA with five use levels of polyethylene glycol (E 1521) in foods for food supplements. Kollisolv, Carbowax, GoLYTELY, GlycoLax, Fortrans, TriLyte, Colyte, Halflytely, Except where otherwise noted, data are given for materials in their. PEG3350, SunMark ClearLax, HealthyLax, Natura-Lax People who already have skin conditions or sensitive skin are at particular risk of contact allergy to this additive (6). Published by Elsevier Inc. All rights reserved. All rights reserved. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. While these reports may be concerning, it is important to note that in both these cases, toxicity occurred due to a high dosage of medication in a vulnerable age group. While PEG and PEO with different molecular weights find use in different applications, and have different physical properties (e.g. In high doses, PEG is a laxative." 4. 17 grams dissolved in 4 to 8 ounces of beverage, orally, once a day Duration of therapy: No more than 7 daysComments:-The beverage may be hot, cold, or room temperature.-Generally produces a bowel movement in 1 to 3 days.Use: Relief of occasional constipation. The Food and Drug Administration (FDA) has classified propylene glycol as an additive that is "generally recognized as safe" for use in food. Because of PEGs hydrophilic nature, it can draw fluid into the intestines and help hydrate stool. Additionally, it can dissolve some substances better than water and is also good at retaining moisture. Polyethylene glycol compounds are whats known as hydrophilic meaning they dissolve in water and tend to attract water.2 Because of its hydrophilic properties, polyethylene glycol has been utilized in many day-to-day products. Polyethylene glycol is a polyether compound, meaning that it consists of multiple ether groups. Polyethylene glycol 3350 normally causes loose or even watery stools. Polyethylene glycol is a free-flowing white powdery substance when it is kept below 55 degrees celsius and is thus easily soluble in water at the same temperature. 1 Polyethylene glycol is not a single chemical entity in and of itself. ", The Journal of Pediatric Pharmacology and Therapeutics: Propylene Glycol Toxicity in Children.. It's also present in many cosmetics, dog food, and hygiene products. . PEG is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. Antifreeze poisoning can lead to serious health complications if not treated early. In addition, propylene glycol can cause irritant contact dermatitis. All rights reserved. PEG is polyethylene glycol, commonly known as the chemical antifreeze in your car. Polyethylene glycol (PEG) is a versatile polymer that is widely used as an additive in foods and cosmetics, and as a carrier in PEGylated therapeutics. It begins to build up in the blood, which interferes with proper functioning (10). And remember, the FDA approval of the Pfizer and Moderna vaccines included a. When used as a laxative, polyethylene glycol is typically taken in powder form mixed with water or juice and can be found under various names including:3. Do not take extra medicine to make up the missed dose. You must not eat anything for 2 hours before starting this medicine. Polyethylene glycol (PEG) is a polymer derived from ethylene oxide is an advantageous component for obtaining solid dispersions due to their physicochemical properties. We present 5 cases of confirmed PEG allergy, which to our knowledge is the largest case series to date. Propylene glycol is commonly used as an additive to aid in the processing of foods and improve their texture, flavor, appearance and shelf life. You see, polyethylene glycol derivatives in and of themselves are not necessarily toxic or dangerous. It is found in many different food products and can be identified by checking the ingredients list. If you have kidney or liver disease, the process of eliminating the compound is also slow. Ethylene glycol and its oligomers are preferable as a starting material instead of water, because they allow the creation of polymers with a low polydispersity (narrow molecular weight distribution). For example, in one study, 19% of critical patients being treated with the drug lorazepam were observed to have signs of propylene glycol toxicity (19). In addition, you can find PEG in foods and food additives. Drug allergy; PEG allergy; Skin test to PEG and anaphylaxis. The amount of medicine that you take depends on the strength of the medicine. Bookshelf Some people still recommend reducing your dietary sources of it, citing the following potential health risks:, Worsenedkidney and liver disease symptoms: If you have normal liver and kidney function, your body can easily remove propylene glycol. 2022 Apr;52(4):578-579. doi: 10.1111/cea.14083. The Foundation for Alternative and Integrative Medicine (FAIM) is a private 501(c)(3) nonprofit foundation. This can lead to a buildup of propylene glycol and lactic acid in the bloodstream, causing symptoms of toxicity (9, 15). While it is a low-toxicity substance, you may develop health complications if you eat foods that have it in large quantities. It is used in the manufacturing of medications such as tablets, capsules, creams, and ointments. The anionic mechanism is preferable because it allows one to obtain PEG with a low polydispersity. Learn what research has found about this controversial ingredient. Propylene glycol is generally recognized as safe (GRAS) by the US Food and Drug Administration (FDA) (8). However, as reported by Murali et al., PEG is very sensitive to sonolytic degradation and PEG degradation products can be toxic to mammalian cells. Polyethylene glycol (PEG) is a biocompatible, synthetic, hydrophilic polyether compound that has many applications, mostly in the medical industry, but also in the chemical and industrial. In comparison, one person who developed symptoms of toxicity was receiving 213 grams of propylene glycol per day. Different forms of polyethylene glycol are usually delineated by placing a number after the abbreviation PEG, such as PEG-100, PEG-3350, and so on. Pregnant women, children and infants under four years of age have lower levels of an enzyme known as alcohol dehydrogenase. There is only one documented case of toxicity caused by food. 2023 Leaf Group Ltd. / Leaf Group Media, All Rights Reserved. 2023 Jan;16(1):100740. doi: 10.1016/j.waojou.2022.100740. Some additives enhance flavor, while others help in food preservation. Both PEG and PG are used in food applications as additives, humectants, and . You should not use polyethylene glycol 3350 if you have a bowel obstruction or intestinal blockage. PEG is a water-soluble, non-ionic compound that is used in a wide range of applications due to its low toxicity, low volatility, and high water solubility. . Optimizing investigation of suspected allergy to polyethylene glycols. Seizures have also been observed in infants who developed toxicity from injectable medications (22). One common ingredient is propylene glycol, primarily found in salad dressing. Take the missed dose as soon as you remember. Since PEG is a flexible, water-soluble polymer, it can be used to create very high, Polyethylene glycol is also commonly used as a polar stationary phase for, PEG has been used to preserve the painted colors on, PEG is often used (as an internal calibration compound) in, PEG has been used as the hydrophilic block of, PEG is a component of the propellent used in, PEG can be modified and crosslinked into a, An example study was done using PEG-diacrylate hydrogels to recreate vascular environments with the encapsulation of, PEG is commonly used as a crowding agent in, PEG is used to fuse two different types of cells, most often B-cells and myelomas in order to create, PEG is also under investigation for use in, PEG is also used as an anti-foaming agent in food and drinks, Dimethyl ethers of PEG are the key ingredient of. Thats why Im dedicated to bringing you easy-to-understand and easy-to-implement tips to take the confusion out of healthy living. Additionally, 16 patients of a neurology clinic were given 402 mg of propylene glycol per pound (887 mg/kg) three times per day for three days. The molecular weight in turn determines the characteristics of each type or category of PEG. The HELP (Hepatic Encephalopathy: Lactulose vs Polyethylene Glycol 3350-Electrolyte Solution) study was approved by the University of Texas Southwestern Medical Center institutional review board and by the Parkland Health and Hospital System. The body breaks down the rest into lactic acid., In large quantities, lactic acid can build up and lead to kidney failure and acidosis. Polyethylene glycol, used as a stabilizer in nanomedicine formulations, has recently been indicated as the possible cause of the anaphylactic reactions against the COVID-19 mRNA-based vaccines . It has practically no taste (1). Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Graduate Medical Education, Mayo Clinic School of Continuous Professional Development, Mayo Clinic on Incontinence - Mayo Clinic Press, NEW Mayo Clinic on High Blood Pressure - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Financial Assistance Documents Minnesota. Because different applications require different polymer chain lengths, PEG has tended to refer to oligomers and polymers with a molecular mass below 20,000g/mol, PEO to polymers with a molecular mass above 20,000g/mol, and POE to a polymer of any molecular mass. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Generic name: polyethylene glycol 3350 [pol-ee-ETH-il-een-GLYE-kol] While these side effects are well-documented, there are growing concerns about other possible polyethylene glycol toxicity symptoms. It has. Symptoms include a slower rate of breathing, decreased heart rate and loss of consciousness (14). Polyethylene glycols (PEGs) are products of condensed ethylene oxide and water that can have various derivatives and functions. Stop taking polyethylene glycol 3350 and call your doctor at once if you have: Common side effects of polyethylene glycol 3350 may include: This is not a complete list of side effects and others may occur. [44], PEG, PEO, and POE refer to an oligomer or polymer of ethylene oxide. government site. However, the majority of foods containing it are highly processed junk foods. Because of their affinity for dissolving in and attracting water, PEGs are regularly utilized in cosmetics as:4,5. Rather it's a category of compounds in which polyethylene and glycol have been bonded together. Ethylene glycol has a sweet taste and is often ingested by accident or on purpose. Propylene glycol is a synthetic food additive that belongs to the same chemical group as alcohol. The molecular weights of PEGs are determined by the number of ethylene glycol units incorporated into each PEG polymer and vary from 300 grams per mole to 10,000,000 grams per mole. The natural red dye is largely made from vegetables like, beetroot, carrots, cherries and elderberries, or it can be obtained from the cochineal insect, known as Dactylopius coccus. Would you like email updates of new search results? Propylene glycol is also used to make polyester compounds, and as a base for deicing solutions. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. And whether or not these side effects also extend to adults and geriatric patients will require further studies as well. Vaccines (Basel). Xanthan gum is a common food additive that has some people worried, while others claim it has health benefits. Copyright 1996-2023 Cerner Multum, Inc. Clin Exp Allergy. they are polydisperse). When ethylene glycol (molecular weight, 62.07) polymerizes, reacts with itself (in water), the reaction yields a variety of products containing varying numbers of ethylene glycol units. PEG can be found in a variety of industrial processes and products, such as:7. However, these are not the same substance. POLYETHYLENE GLYCOL (pol ee ETH i leen; GLYE col) prevents and treats occasional constipation. But though it is considered generally safe for human and animal consumption, cats have a unique sensitivity to propylene glycol and . Careers. Polyethylene is a member of the important family of polyolefin resins. viscosity) due to chain length effects, their chemical properties are nearly identical. Available for Android and iOS devices. Clipboard, Search History, and several other advanced features are temporarily unavailable. Do you have a history of an immediate (<4 h) or severe allergic reaction to polyethylene glycol (PEG), a polysorbate or polyoxyl 35 castor oil (e.g. However, there are some simple yet powerful steps you can take to protect yourself against polyethylene glycol and other harmful toxins. However, a growing body of evidence shows the existence of a detectable level of anti-PEG antibodies in approximately 72% of the population, never treated with PEGylated drugs, based on plasma samples from 1990 to 1999. PEG3350, SunMark ClearLax, HealthyLax, Natura-Lax. The numbers that are often included in the names of PEGs indicate their average molecular weights (e.g. Moreover, there are no reported deaths on record (1, 9). chemical waste image by Antonio Oquias from Fotolia.com. However, another study demonstrated that doses of up to 15.4 mg per pound (34 mg/kg) of propylene glycol over 24 hours were tolerated by young babies (24). It works by causing water to be retained with the stool. Propylene glycol is a colorless, nearly odorless, thick liquid. The names it may be listed under include: Common foods include soft drinks, marinades and dressings, cake mix, frosting, popcorn, food coloring, fast foods, bread and dairy products (6, 35). 2021 Jun;61(6):832-835. doi: 10.1002/jcph.1824. It is, thus, imperative to assess potential PEG degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.[51]. The possibility that PEG could be used to fuse. FAIM depends on public donations to continue its work. The two OH groups lead to extensive . Because of this reported increase in neuropsychiatric side effects, parents and pediatric practitioners are becoming increasingly wary of administering polyethylene glycol to adolescents. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Do not add starch-based thickeners to this medicine. Subscribe to our monthly free email newsletter, 2009-2022 Foundation for Alternative and Integrative Medicine | Contact us, Foundation for Alternative and Integrative Medicine, #ChemicalCallout: Polyethylene Glycol Compounds (PEGs) (madesafe.org), Polyethylene Glycol StatPearls NCBI Bookshelf (nih.gov), Polyethylene glycol 3350 Uses, Side Effects & Warnings Drugs.com, The Dirty Dozen: PEG Compounds and their contaminants David Suzuki Foundation, Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use (nih.gov), Polyethylene Glycol-Induced Systemic Allergic Reactions (Anaphylaxis) PubMed (nih.gov), Common and Rare Side Effects for polyethylene glycol 3350 oral (webmd.com), Probable neuropsychiatric toxicity of polyethylene glycol: roles of media, internet and the caregivers Hussain 2019 GastroHep Wiley Online Library, Pharmaceutical and Over-the-Counter Drugs, As cell-penetrating enhancers in vaccines. chemical waste image by Antonio Oquias from, RxList: MiraLAX (Polyethylene Glycol 3350). One woman with kidney damage was treated for short breath and throat swelling with lorazepam. The Use of Ionic Copper in the Treatment of Arthritis, David Attenborough's Wild City - Episode 2: Urban Wild, David Attenborough's Wild City - Episode 1: Hidden Wild. Different forms of PEG are also available, depending on the initiator used for the polymerization process the most common initiator is a monofunctional methyl ether PEG, or methoxypoly(ethylene glycol), abbreviated mPEG. A fresh, whole foods diet will naturally contain lower amounts of this additive. A man drank very large amounts of cinnamon whiskey containing propylene glycol and was found unconscious. Polyethylene glycol compounds are widespread in household products from skin care and cosmetics, to baby wipes and cleaners. The dose of this medicine will be different for different patients. But Im a firm believer in being proactive and protective when it comes to your health. If you are using the bottle, measure the powder with the measuring cap (bottle top). This number represents the molecular weight of that specific compound. It is an odorless, colorless, flammable, viscous liquid. Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight polyethylene glycol.[54]. Written by Cerner Multum. Four of the 5 cases developed anaphylaxis to medications con It is not known whether polyethylene glycol 3350 passes into breast milk or if it could harm a nursing baby. 2015 Mar;45(3):669-76. doi: 10.1111/cea.12441. FIND PRODUCTS WITH THIS INGREDIENT. Welcome to Life Without Glycols! In another case, a 15-month-old child was given oral doses of vitamin C dissolved in propylene glycol.

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